منابع مشابه
Dapsone-induced methemoglobinemia: case of the blue lady.
Methemoglobinemia is a life-threatening condition that can be difficult to diagnose. While methemoglobinemia can be congenital and should be considered in cyanotic infants,1 it is more often an adverse medication effect, most commonly related to dapsone use.2 As up to 1 in 9 emergency department visits in Canada might be owing to adverse medication effects, physicians and other health care prov...
متن کاملMethemoglobinemia as a complication of topical dapsone.
n engl j med 372;5 nejm.org january 29, 2015 491 tion techniques used by high-reliability organizations, the I-PASS mnemonic offers a predictable structure that enhances the process of information transfer.1,2 However, we hypothesized that to effect significant, sustainable change, we needed to change institutional handoff culture substantively at the same time that we introduced the mnemonic. ...
متن کاملMethemoglobinemia caused by dapsone overdose: Which treatment is best?
Increase of methemoglobin level is named as methemoglobinemia characterized by functional anemia and tissue hypoxia. Methemoglobinemia can be congenital, but acquired form are more often caused by various drugs and toxins. Methylene blue is the most effective antidote for acquired methemoglobinemia. When methylene blue is not available, alternative treatments such as ascorbic acid and hyperbari...
متن کاملIdentifying the Cause of the "Saturation Gap": Two Cases of Dapsone-induced Methemoglobinemia.
Diaphenylsulfone (DDS: Dapsone) is used for Pneumocystis pneumonia (PCP) prophylaxis, and methemoglobinemia has rarely been reported as a side effect of DDS. We herein report two cases of DDS-related methemoglobinemia in an 81-year-old man with organizing pneumonia and an 84-year-old woman with eosinophilic pneumonia under treatment with prednisolone. Both patients initially received trimethopr...
متن کاملAcute Dapsone-Induced Methemoglobinemia in a 24-Year-Old Woman with Ulcerative Colitis
www.turner-white.com M ethemoglobin, a unique form of hemoglobin (Hb) with diminished oxygen affinity, is formed and metabolized roughly at equivalent rates under normal physiologic conditions. However, when methemoglobin generation supersedes compensatory physiologic reductive capacity, methemoglobinemia may result. Potential etiologies of methemoglobinemia include a variety of heritable metab...
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ژورنال
عنوان ژورنال: Cancer
سال: 2011
ISSN: 0008-543X
DOI: 10.1002/cncr.25904